Listar por autor "Garesse, Rafael"

Mostrando ítems 1-3 de 3

    • Generating Rho-0 cells using mesenchymal stem cell lines 

      Fernández-Moreno, Mercedes; Hermida Gómez, Tamara; Gallardo, M. Esther; Dalmao-Fernández, Andrea; Rego-Pérez, Ignacio; Garesse, Rafael; Blanco García, Francisco J (PLoS, 2016-10-20)
      [Abstract] Introduction, The generation of Rho-0 cells requires the use of an immortalization process, or tumor cell selection, followed by culture in the presence of ethidium bromide (EtBr), incurring the drawbacks its ...

    • Mitochondrial DNA from osteoarthritic patients drives functional impairment of mitochondrial activity: a study on transmitochondrial cybrids 

      Dalmao-Fernández, Andrea; Hermida Gómez, Tamara; Lund, Jenny; Vázquez-Mosquera, María E.; Rego-Pérez, Ignacio; Garesse, Rafael; Blanco García, Francisco J; Fernández-Moreno, Mercedes (Elsevier, 2022-05)
      [Abstract] With the redefinition of osteoarthritis (OA) and the understanding that the joint behaves as an organ, OA is now considered a systemic illness with a low grade of chronic inflammation. Mitochondrial dysfunction ...

    • Mitochondrial DNA haplogroups influence the risk of incident knee osteoarthritis in OAI and CHECK cohorts: a meta-analysis and functional study 

      Fernández-Moreno, Mercedes; Soto-Hermida, Ángel; Vázquez-Mosquera, María E.; Cortés-Pereira, Estefanía; Relaño, Sara; Hermida Gómez, Tamara; Pértega-Díaz, Sonia; Oreiro, Natividad; Fernández-López, Carlos; Garesse, Rafael; Blanco García, Francisco J; Rego-Pérez, Ignacio (BMJ, 2016-12-05)
      [Abstract] Objective To evaluate the influence of the mitochondrial DNA (mtDNA) haplogroups in the risk of incident knee osteoarthritis (OA) and to explain the functional consequences of this association to identify potential ...